May Colloquium Seminar Session
Chair: Adelaide Jewell
12:05: Ben Fielder
Title: Targeted liposomes for drug delivery to intracellular pathogens
Abstract: Some bacteria have evolved to 'hide' within our immune cells, shielding them other immune cells and drugs. My project hopes to develop antibiotic-filled liposomes (a type of nanoparticle) that are targeted to deliver drugs specifically to these intracellular bacteria.
12:20: Savvas Dimiou
Title: Inhaling genes: A non-invasive route to deliver therapeutics to the body
Abstract: The pulmonary delivery of nucleic acids has considerable potential for therapeutic and vaccine applications. Here we investigate the use of nucleic acid dry powder formulations with the aim of making gene therapy non-invasive
12:35: Monika Myślińska
Title: Amorphous solid dispersions - comparison of methods of production and impact of downstream processing on drug product performance
Abstract: The aim of this PhD project is to compare the solid-state properties and physical stability of amorphous solid dispersions (ASDs) produced by different manufacturing techniques. The differences in ASD properties are analysed by a range of analytical techniques such as: differential scanning calorimetry, thermogravimetric analysis, particle size distribution analysis, powder X-ray diffraction and Fourier transform infrared spectroscopy
12:50: Laura McCoubrey
Title: Harnessing AI to predict medicine-microbiome interaction
Abstract: Evidence is increasingly revealing the importance of the drug-microbiome relationship for human health and response to medicines. Machine learning techniques have the power to detect, analyse, and predict medicine-microbiome interactions, for the ultimate benefit of patient care.
13:05: Toby King
Title: Stabilizing therapeutic protein solutions: optimisation of excipient properties using computational modelling and synthetic chemistry
Abstract:
13:20: Nour Allahham
Title:
Abstract: